15(S)-Latanoprost, CAS 145773-22-4

Formulation: A solution in methyl acetate

Formal Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic acid, 1-methylethyl ester

Purity: ≥98%

Formula Markup: C26H40O5

Formula Weight: 432,6

Shelf life (days): 730

CAS Number: 145773-22-4

Notes: 15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.{9736} A 3 µg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.{9736} 15(S)-Latanoprost is a potential impurity in most commercial preparations of the latanoprost bulk drug product.

• Artikelnummer: CAY16818-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16818-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK