(±)16-HETE, CAS 128914-46-5

Formulation: A solution in ethanol

Formal Name: (±)16-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid

Purity: ≥98%

Formula Markup: C20H32O3

Formula Weight: 320,5

Shelf life (days): 730

CAS Number: 128914-46-5

Notes: Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)16-HETE is the racemic version of a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation. The biological activity of 16-HETE is stereospecific. 16(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, however 16(S)-HETE does not affect perfusion pressure.{3825} At a concentration of 2 µM the (S)-enantiomer of 16-HETE inhibits proximal tubule ATPase activity by as much as 60%, whereas the (R)-isomer has negligible effects on ATPase activity.{3825}

• Artikelnummer: CAY10010635-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10010635-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK