16-Ketoestradiol, CAS 566-75-6

Formulation: A solid

Formal Name: 3,17β-dihydroxy-estra-1,3,5(10)-trien-16-one

Purity: ≥95%

Formula Markup: C18H22O3

Formula Weight: 286,4

Shelf life (days): 1460

CAS Number: 566-75-6

Notes: 16-Ketoestradiol is an active metabolite of the endogenous estrogen estrone (Item No. 10006485).{60391} It is formed from estrone via an estriol (Item No. 10006484) or a 16-epiestriol (Item No. 33455) intermediate by oxidation of the C-16 hydroxyl. 16-Ketoestradiol binds to estrogen receptor α (ERα) and ERβ with IC50 values of 112.2 and 50.1 nM for the human receptors, respectively.{65163} Intravaginal administration of 16-ketoestradiol increases vaginal epithelial thickness, stratification, and cornification in mice, indicating antiestrogenic activity.{65164}

• Artikelnummer: CAY36033
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36033-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe