(±)17-HDHA, CAS 90780-52-2

Formulation: A solution in ethanol

Formal Name: (±)17-hydroxy-4Z,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid

Purity: ≥98%

Formula Markup: C22H32O3

Formula Weight: 344,5

Shelf life (days): 730

CAS Number: 90780-52-2

Notes: (±)17-HDHA is an autoxidation product of docosahexaenoic acid (DHA; Item No. 90310) in vitro.{7479,7491} It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.{7480,7490,7492} 17(S)-HDHA (Item No. 10009799) could be produced by enzymatic oxidation of DHA using soybean lipoxygenase (LO) and is the putative product of mammalian 15-LOs.{7492} 17(S)-HDHA was shown to be an inhibitor of U-46619 (Item No. 16450) -induced rabbit and rat aortic smooth muscle contraction with IC50 values of 4.9 and 7.2 µM, respectively.{7481} (±)17-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.

• Artikelnummer: CAY33650-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33650-25
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK