Formulation: A solution in ethanol
Formal Name: (±)17-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid
Purity: ≥98%
Formula Markup: C20H32O3
Formula Weight: 320,5
Shelf life (days): 730
CAS Number: 128914-47-6
Notes: Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 µM the (S)-enantiomer of 17-HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R)-isomer is inactive.{3825}