Formulation: A crystalline solid
Formal Name: 9α,11α,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-cyclopropyl methyl amide
Purity: ≥98%
Formula Markup: C27H39NO4
Formula Weight: 441,6
Shelf life (days): 730
CAS Number: 1138395-10-4
Notes: Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α.{2058} It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2α ethyl amide.{12894} 17-phenyl trinor PGF2α ethyl amide is used to reduce intraocular pressure related to glaucoma.{12188} 17-phenyl trinor PGF2α cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2α. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.