17-phenyl trinor Prostaglandin F2α-d4, CAS 58976-50-4

Formulation: A solution in methyl acetate

Formal Name: 9α,11α,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C23H28D4O5

Formula Weight: 392,5

Shelf life (days): 730

CAS Number: 58976-50-4

Notes: 17-phenyl trinor Prostaglandin F2α-d4 (17-phenyl trinor PGF2α-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 17-phenyl trinor PGF2α by GC- or LC-mass spectrometry. 17-phenyl trinor PGF2α is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. It binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α.{2058} At the rat recombinant FP receptor expressed in CHO cells 17-phenyl trinor PGF2α inhibits PGF2α binding with a Ki of 1.1 nM.{1374} The isopropyl ester of 17-phenyl trinor PGF2α-d4 is slightly better than PGF2α isopropyl ester in reducing the intraocular pressure in the cat eye without any irritation.{1107}

• Artikelnummer: CAY316810-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 316810-25
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung