Formulation: A crystalline solid
Formal Name: N-ethyl-9α,11α,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-amide
Purity: ≥97%
Formula Markup: C25H37NO4
Formula Weight: 415,6
Shelf life (days): 730
CAS Number: 155206-00-1
Notes: 17-phenyl trinor Prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide) is an F-series prostaglandin derivative and an agonist of FP receptors.{9581,8941} It induces calcium mobilization in 3T3-L1 fibroblasts expressing the human receptors (EC50 = 2.2 µM).{9581} Ocular administration of 17-phenyl trinor PGF2α ethyl amide (0.03% w/v) reduces intraocular eye pressure (IOP) in normotensive dogs and ocular hypertensive monkeys.{8941} Formulations containing 17-phenyl trinor PGF2α ethyl amide have been used in the treatment of open angle glaucoma, ocular hypertension, and eyelash hypotrichosis.