17-phenyl trinor Prostaglandin F2α ethyl amide-d4

Formulation: A solution in methyl acetate

Formal Name: N-ethyl-9α,11α,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-amide-3,3,4,4-d4

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C25H33D4NO4

Formula Weight: 419,6

Shelf life (days): 730

Notes: 17-phenyl trinor Prostaglandin F2α ethyl amide-d4 is intended for use as an internal standard for the quantification of 17-phenyl trinor prostaglandin F2α ethyl amide (Item No. 16820) by GC- or LC-MS. 17-phenyl trinor Prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide) is an F-series prostaglandin derivative and an agonist of FP receptors.{9581,8941} It induces calcium mobilization in 3T3-L1 fibroblasts expressing the human receptors (EC50 = 2.2 µM).{9581} Ocular administration of 17-phenyl trinor PGF2α ethyl amide (0.03% w/v) reduces intraocular eye pressure (IOP) in normotensive dogs and ocular hypertensive monkeys.{8941} Formulations containing 17-phenyl trinor PGF2α ethyl amide have been used in the treatment of open angle glaucoma, ocular hypertension, and eyelash hypotrichosis.

• Artikelnummer: CAY316820-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 316820-25
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung