17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α, CAS 294856-01-2

Formulation: A solution in methyl acetate

Formal Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pentyl]cyclopentyl]-5-heptenoic acid

Purity: ≥98%

Formula Markup: C24H33O5F3

Formula Weight: 458,5

Shelf life (days): 365

CAS Number: 294856-01-2

Notes: A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.{8941,9341,8839} Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects.{9736} 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2α would act very much like the free acid of latanoprost.

• Artikelnummer: CAY16895-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16895-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK