17R(18S)-EpETE, CAS 725246-18-4

Formulation: A solution in ethanol

Formal Name: 16-[(2R,3S)-3-ethyl-2-oxiranyl]-5Z,8Z,11Z,14Z-hexadecatetraenoic acid

Purity: ≥95%

Formula Markup: C20H30O3

Formula Weight: 318,5

Shelf life (days): 730

CAS Number: 725246-18-4

Notes: 17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid (EPA; Item Nos. 90110 / 90110.1 / 21908).{11951,9825} 17R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (KCa1.1/BK) channels, increasing the potassium current amplitude by 15-fold in isolated rat cerebral artery vascular smooth muscle cells (VSMCs) at +60 mV when used at a concentration of 50 nM.{9825} It has negative chronotropic effects in isolated neonatal rat cardiomyocytes (NRCMs; EC50 = ~1-2 nM) and prevents calcium-induced increases in the spontaneous beating of NRCMs.{19905,18672}

• Artikelnummer: CAY28630-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 28630-25
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK