(±)18-HEPE, CAS 141110-17-0

Formulation: A solution in ethanol

Formal Name: (±)-18-hydroxy-5Z,8Z,11Z,14Z,16E-eicosapentaenoic acid

Purity: ≥97%

Formula Markup: C20H30O3

Formula Weight: 318,5

Shelf life (days): 365

CAS Number: 141110-17-0

Notes: (±)18-HEPE is produced by non-enzymatic oxidation of eicosapentaenoic acid (EPA; Item Nos. 90110 / 90110.1 / 21908).{53027} 18-HEPE levels are increased in the plasma and heart, as well as in the supernatant of cultured peritoneal macrophages isolated from fat-1 transgenic mice that are capable of endogenously producing ω-3 fatty acids from ω-6 fatty acids.{53024,53025,53026} It reduces increases in cardiac fibrosis and the expression of Nppa, Col1a1, Tgfb1, Cx3cl1, and Adgre1 induced by transverse aortic constriction in a mouse model of cardiac hypertrophy when administered at doses of 1 and 5 µg.{53025}

• Artikelnummer: CAY32840-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 32840-50
• Green Labware: Nein
• Verpackungseinheit: 50 µg
• Mengeneinheit: STK