2-Arachidonoyl Glycerol-d8, CAS 924894-97-3

Formulation: A solution in acetonitrile

Formal Name: 5Z,8Z,11Z,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid, 2-glyceryl ester

Purity: ≥99% deuterated forms (d1-d8)

Formula Markup: C23H30D8O4

Formula Weight: 386,6

Shelf life (days): 365

CAS Number: 924894-97-3

Notes: 2-Arachidonoyl glycerol-d8 (2-AG-d8) is intended for use as an internal standard for the quantification of 2-AG (Item No. 62160) by GC- or LC-MS. 2-AG is an endogenous agonist of the CB1 receptor.{7183,7182} Unlike anandamide, 2-AG is present at relatively high levels in the central nervous system; it is the most abundant molecular species of monoacylglycerol found in rat brain.{7183,6819} Formation of 2-AG is calcium-dependent and is mediated by the activities of phospholipase C and diacylglycerol lipase.{7183} 2-AG acts as a full agonist at the CB1 receptor. At a concentration of 0.3 nM, 2-AG induces a rapid, transient increase in intracellular free calcium in NG108-15 neuroblastoma X glioma cells through a receptor-dependent mechanism.{5306}

• Artikelnummer: CAY362160-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 362160-50
• Green Labware: Nein
• Verpackungseinheit: 50 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung