21-Deoxycortisol-d8, CAS 2479914-04-8

Formulation: A crystalline solid

Formal Name: 11,17-dihydroxy-pregn-4-ene-3,20-dione-2,2,4,6,6,21,21,21-d8

Purity: ≥99% deuterated forms (d1-d8)

Formula Markup: C21H22D8O4

Formula Weight: 354,5

Shelf life (days): 1460

CAS Number: 2479914-04-8

Notes: 21-Deoxycortisol-d8 is intended for use as an internal standard for the quantification of 21-deoxycortisol (Item No. 30873) by GC- or LC-MS. 21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal gland via 11-hydroxylation by 11β-hydroxylase.{56104,56105} Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations in CYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies.

• Artikelnummer: CAY35556-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35556-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung