3-Hydroxyglutaric Acid, CAS 638-18-6

Formulation: A crystalline solid

Formal Name: 3-hydroxy-pentanedioic acid

Purity: ≥95%

Formula Markup: C5H8O5

Formula Weight: 148,1

Shelf life (days): 1460

CAS Number: 638-18-6

Notes: Glutaryl-CoA dehydrogenase (GCDH) is a mitochondrial matrix protein that catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and carbon dioxide in the catabolic pathways of lysine, hydroxylysine, and tryptophan metabolism.{13906} 3-Hydroxyglutaric acid is one of several metabolites produced when insufficient levels of GCDH are available.{16334,13906} Urinary levels of 3-hydroxyglutaric acid are elevated during glutaric acidemia type 1, an autosomal recessive GCDH deficiency disorder that can lead to neurodegeneration if left untreated.{16334,13906} 3-Hydroxyglutaric acid is used as a biomarker of GCDH deficiency.{16334,13906}

• Artikelnummer: CAY16334-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16334-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK