3β-hydroxy-5-Cholestenoic Acid, CAS 6561-58-6

Formulation: A solid

Formal Name: (3β)-3-hydroxy-cholest-5-en-26-oic acid

Purity: ≥95%

Formula Markup: C27H44O3

Formula Weight: 416,6

Shelf life (days): 1460

CAS Number: 6561-58-6

Notes: 3β-hydroxy-5-Cholestenoic acid is an active metabolite of cholesterol formed when cholesterol is metabolized by the cytochrome P450 (CYP) isomer CYP27A1.{41086} 3β-hydroxy-5-Cholestenoic acid is a modulator of γ-secretase that decreases amyloid β (1-42) peptide (Aβ42; EC50 = 250 nM) and increases Aβ38 levels with no effect on total Aβ in CHO2B7 cells. It decreases endogenous murine Aβ42 production by 60 and 75% in mouse postnatal neuron-glia cultures at concentrations of 3 and 10 μM, respectively.

• Artikelnummer: CAY21859-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21859-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK