4-hydroxy Nonenal Alkyne, CAS 1011268-23-7

Formulation: A solution in methyl acetate

Formal Name: 4-hydroxynon-2E-nonen-8-ynal

Purity: ≥98%

Formula Markup: C9H12O2

Formula Weight: 152,2

Shelf life (days): 365

CAS Number: 1011268-23-7

Notes: 4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid.{869,1103} It is considered a potential causal agent in numerous diseases, including chronic inflammation, neurodegenerative diseases, atherosclerosis, diabetes, and cancer, in part because it covalently modifies DNA and proteins resulting in genetic mutations and altered cell signaling, respectively.{18126} 4-HNE alkyne is a form of 4-HNE with a terminal alkyne. Such terminal alkyne groups can be used in linking reactions, known as click chemistry, characterized by high dependability and specificity of azide-alkyne bioconjugation reactions.{17991,17992}

• Artikelnummer: CAY13265-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 13265-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Click Chemistry