4β-hydroxy Cholesterol, CAS 17320-10-4

Formulation: A crystalline solid

Formal Name: cholest-5-ene-3β,4β-diol

Purity: ≥95%

Formula Markup: C27H46O2

Formula Weight: 402,7

Shelf life (days): 730

CAS Number: 17320-10-4

Notes: 4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation.{31450} It is formed from cholesterol by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5.{31450} 4β-hydroxy Cholesterol has an unusually long half-life in plasma (~60 hours) as a result of slow elimination, particularly due to a slow rate of 7α-hydroxylation, which is the rate-limiting step for further conversion into bile acids.

• Artikelnummer: CAY19518-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 19518-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK