4β-hydroxy Cholesterol-d7, CAS 1246302-80-6

Formulation: A solid

Formal Name: cholest-5-ene-25,26,26,26,27,27,27-d7-3β,4β-diol

Purity: ≥99% deuterated forms (d1-d7)

Formula Markup: C27H39D7O2

Formula Weight: 409,7

Shelf life (days): 1460

CAS Number: 1246302-80-6

Notes: 4β-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 4β-hydroxy cholesterol (Item No. 19518) by GC- or LC-MS. 4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation.{31450} It is formed from cholesterol by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5.{31450} 4β-hydroxy Cholesterol has an unusually long half-life in plasma (~60 hours) as a result of slow elimination, particularly due to a slow rate of 7α-hydroxylation, which is the rate-limiting step for further conversion into bile acids.

• Artikelnummer: CAY25971-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 25971-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung