Formulation: A crystalline solid
Formal Name: 5,8,11-eicosatriynoic acid
Purity: ≥95%
Formula Markup: C20H28O2
Formula Weight: 300,4
Shelf life (days): 1460
CAS Number: 13488-22-7
Notes: 5,8,11-ETI is a nonselective inhibitor of lipoxygenases. It inhibits 12-LO in human platelets with an ID50 value of 24 µM.{66} 5,8,11-ETI also inhibits A23187 and L-cysteine induced LTC4 biosynthesis in mouse mastocytoma cells with an ID50 value of 5 µM.{650} At higher concentrations, 5,8,11-ETI also inhibits cyclooxygenases (ID50 = 340 µM).{66}