5-cis Carbaprostacyclin, CAS 69609-77-4

Formulation: A crystalline solid

Formal Name: (5Z)-5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-1-octenyl]-2(1H)-pentalenylidene]-pentanoic acid

Purity: ≥99%

Formula Markup: C21H34O4

Formula Weight: 350,5

Shelf life (days): 365

CAS Number: 69609-77-4

Notes: 5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin. It is a weak inhibitor of human platelet aggregation with an IC50 of 2.8 µM compared to 0.3 µM for carbaprostacyclin.{509,3320} 5-cis Carbaprostacyclin is a much weaker effector of rabbit mesenteric artery relaxation with an EC50 of 104 µM compared to 5.9 µM for carbaprostacyclin. It even antagonizes the adenylate cyclase activation induced by carbaprostacyclin.{3320}

• Artikelnummer: CAY18211-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 18211-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK