(±)5-iPF2α-VI, CAS 179094-11-2

Formulation: A solution in ethanol

Formal Name: (8β)-5,9α,11α-trihydroxy-prosta-6E,14Z-dien-1-oic acid

Purity: ≥95%

Formula Markup: C20H34O5

Formula Weight: 354,5

Shelf life (days): 365

CAS Number: 179094-11-2

Notes: Isoprostanes are prostaglandin (PG)-like products of free-radical induced lipid peroxidation.{320} Although the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can form isoprostanes.{7323} (±)5-iPF2α-VI is one of dozens of possible stereo- and regioisomeric isoprostanes which can be formed from arachidonic acid. To date, the most extensively studied of these is 8-isoprostane (8-epi-PGF2α, iPF2α-III).{3064,5011} However, 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers which form in natural conditions of oxidative stress.{8367} (±)5-iPF2α-VI is an isoprostane from the unique Type VI class of isoprostanes. This class has been shown to be one of the major isoprostane products, in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane, Type VI isoprostanes form internal lactones, which facilitates their extraction and purification from biological samples.{8367,9408,6910,6390}

• Artikelnummer: CAY16300-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16300-25
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK