5-POHSA-d14, CAS 2749982-66-7

Formulation: A solution in methyl acetate

Formal Name: 5-[[(9Z)-1-oxo-9-hexadecen-1-yl-2,2,3,3,4,4,5,5,6,6,7,7,8,8-d14]oxy]-octadecanoic acid

Purity: ≥95% deuterated forms (d1-d14)

Formula Markup: C34H50D14O4

Formula Weight: 551

Shelf life (days): 365

CAS Number: 2749982-66-7

Notes: 5-POHSA-d14 is intended for use as an internal standard for the quantification of 5-POHSA (Item No. 17114) by GC- or LC-mass spectrometry. Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity in mice.{27644} Structurally these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to either a C-16 or C-18 hydroxy substituent. 5-POHSA is a FAHFA consisting of palmitoleic acid esterified at the 5th carbon of hydroxy stearic acid. The levels of POHSA are significantly elevated in serum of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue.{27644} As other FAHFA improve glucose tolerance, stimulate insulin secretion, and have anti-inflammatory effects, 5-POHSA may be a bioactive lipid with roles in metabolic syndrome and inflammation.{27644}

• Artikelnummer: CAY17196-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 17196-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung