6α-Prostaglandin I1, CAS 62777-90-6

Formulation: A crystalline solid

Formal Name: 6R,9α-epoxy-11α,15S-dihydroxy-prost-13E-en-1-oic acid

Purity: ≥99%

Formula Markup: C20H34O5

Formula Weight: 354,5

Shelf life (days): 730

CAS Number: 62777-90-6

Notes: 6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration dependent manner. However, it is about 10-fold less potent than the β-isomer and 100-fold less potent than PGI2 in eliciting the response.{11172} 6α-PGI1 exhibits an IC50 of 350 ng/ml for inhibition of ADP-induced platelet aggregation, which is nearly 900-fold higher than that observed for PGI2 (0.4 ng/ml).{11183}

• Artikelnummer: CAY18110-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 18110-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK