Notes: 7α-hydroxy Dehydroepiandrosterone (7α-hydroxy DHEA) is an active metabolite of the endogenous steroid hormone dehydroepiandrosterone (Item No. 15728).{63031} 7α-hydroxy DHEA is formed from dehydroepiandrosterone via 7-hydroxylation by cytochrome P450s (CYPs).{63032} It increases antigen-induced production of anti-tetanus toxoid and anti-pertussis antigen IgGs in co-cultures of human tonsil-derived B and T cells when used at a concentration of 1 µM.{63033} 7α-hydroxy DHEA (6.25 mg/kg) increases serum concentrations of anti-lysozyme IgG in mice.{63031}