Formulation: A solution in ethanol
Formal Name: 8,9-dihydroxy-5Z,11Z,14Z,17Z-eicosatetraenoic acid
Purity: ≥98%
Formula Markup: C20H32O4
Formula Weight: 336,5
Shelf life (days): 730
CAS Number: 867350-87-6
Notes: (±)8(9)-DiHETE is a major metabolite of the 20:5 ω-3 fatty acid eicosapentaenoic acid (EPA; Item No. 90110).{13149} It is produced in rat liver microsomes, but not renal microsomes, by the generation of the unstable intermediate 8,9-epoxy eicosatetraenoic acid from EPA by cytochrome P450 monooxygenases.{13149} Dietary EPA supplementation in humans results in substantial urinary excretion of vicinal diols, including 8,9, 11,12, and 14,15 forms.{996}