9(E),11(E),13(E)-Octadecatrienoic Acid, CAS 544-73-0

Formulation: A solution in methanol

Formal Name: 9E,11E,13E-octadecatrienoic acid

Purity: ≥97%

Formula Markup: C18H30O2

Formula Weight: 278,4

Shelf life (days): 365

CAS Number: 544-73-0

Notes: 9(E),11(E),13(E)-Octadecatrienoic acid (β-ESA) is a conjugated polyunsaturated fatty acid that is found in plant seed oils and in mixtures of conjugated linolenic acids synthesized by the alkaline isomerization of linolenic acid.{37085} It reduces growth of Caco-2 colon cancer cells in a dose-dependent and time-dependent manner. In vitro, β-ESA induces DNA fragmentation and upregulation of pro-apoptotic Bax mRNA. β-ESA decreases protein expression of the apoptosis suppression factor Bcl-2 and induces apoptosis in T24 bladder cancer cells via production of reactive oxygen species.{37086} It also inhibits bacterial fatty acid dioxygenase with a Ki value of 49 nM in vitro.{37087}

• Artikelnummer: CAY22976-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 22976-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK