α-GalCer analog 8, CAS 922727-14-8

Formulation: A solid

Formal Name: (2S,3S,4R)-3,4-dihydroxy-2-(4-tetracosyl-1H-1,2,3-triazol-1-yl)octadecyl, α-D-galactopyranoside

Purity: ≥95%

Formula Markup: C50H97N3O8

Formula Weight: 868,3

Shelf life (days): 1460

CAS Number: 922727-14-8

Notes: α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide.{42588} It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 (Item No. 11208) in mouse splenocytes in vitro and in mouse serum following administration of a 1 µg per animal dose, indicating a Th2 response.

• Artikelnummer: CAY26660
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 26660-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK