Abiraterone, CAS 154229-19-3

Formulation: A crystalline solid

Formal Name: (3β)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol

Purity: ≥98%

Formula Markup: C24H31NO

Formula Weight: 349,5

Shelf life (days): 1460

CAS Number: 154229-19-3

Notes: Abiraterone is an inhibitor of the cytochrome P450 (CYP) isoform CYP17A1 (IC50s = 0.0029 and 0.004 µM for the 17,20-lyase and 17α-hydroxylase activities, respectively) and active metabolite of abiraterone acetate (Item No. 15148).{24420,24421} It is formed from abiraterone acetate by arylacetamide deacetylase.{61882} Abiraterone is selective for CYP17A1 over aromatase and 5α-reductase (IC50s = >20 and >50 µM, respectively).{24420}

• Artikelnummer: CAY9002768-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 9002768-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK