Aflatoxin B1, CAS 1162-65-8

Formulation: A crystalline solid

Formal Name: 2,3,6aR,9aS-tetrahydro-4-methoxy-1H,11H-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione

Purity: ≥98%

Formula Markup: C17H12O6

Formula Weight: 312,3

Shelf life (days): 730

CAS Number: 1162-65-8

Notes: Aflatoxin B1 (AFB1) is a genotoxic mycotoxin that has been found in Aspergillus.{52844,20403} It induces the formation of DNA adducts in rat liver microsomes.{52844} AFB1 induces transversion of guanine to thymine at codon 29 of the p53 tumor suppressor gene, a mutation commonly seen in hepatocellular carcinoma patients living in regions with high levels of aflatoxin contamination, in HepG2 cells.{20403} In vivo, AFB1 (50 and 100 µg/kg) induces hepatocellular carcinoma tumor formation in rats.{52845}

• Artikelnummer: CAY11293-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 11293-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK