Formulation: A solution in ethanol
Formal Name: N-(4-hydroxyphenyl)-5Z,8Z,11Z,14Z-eicosatetrenamide
Purity: ≥98%
Formula Markup: C26H37NO2
Formula Weight: 395,6
Shelf life (days): 365
CAS Number: 183718-77-6
Notes: AM404 is an analog of arachidonyl ethanolamide (AEA) which potentiates the activity of endogenous AEA by blocking its re-uptake into presynaptic neurons. AM404 selectively inhibits the carrier-mediated transport of AEA without affecting anandamide hydrolysis. It inhibits the transport of AEA with an IC50 of 1 µM in rat neurons and 5 µM in rat astrocytes. In in vivo models, AM404 enhances and prolongs exogenous AEA-induced analgesia at a dose of 10 mg/kg.{4894}