Amentoflavone, CAS 1617-53-4

Formulation: A crystalline solid

Formal Name: 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Purity: ≥98%

Formula Markup: C30H18O10

Formula Weight: 538,5

Shelf life (days): 1460

CAS Number: 1617-53-4

Notes: Amentoflavone is a biflavonoid originally isolated from Selaginella. It has a wide variety of biological effects including antibacterial, antioxidant, antiviral, antidiabetic, and neuroprotective activities.{39073,36059,39075,39078} Amentoflavone has antiviral activity against the influenza A subtypes H1N1 and H3N2, influenza B, and herpes simplex virus 1 (EC50s = 3.1 and 4.3, 0.56, and 17.9 µg/ml, respectively).{39076} It has antidiabetic effects such that it dose-dependently increases insulin receptor phosphorylation and activation and inhibits hydrolysis of p-nitrophenyl phosphate (p-NPP) catalyzed by protein tyrosine phosphatase 1B (PTP1B; IC50 = 7.3 µM).{39077} Amentoflavone reduces the time mice spend immobile in the forced swim test, a measure of antidepressant efficacy, in a dose-dependent manner.{39074}

• Artikelnummer: CAY21779-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21779-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK