Amycolatopsin A, CAS 2209112-96-7

Formulation: A solid

Formal Name: (3E,5E,7E,11E,13E,15E)-20-((R)-1-((2S,3R,4R,5S,6R)-5-(((2S,4S,5S,6R)-5-(((2S,4R,5R,6R)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,4-dihydroxy-3-methoxy-6-(3-methoxypropyl)-5-methyltetrahydro-2H-pyran-2-yl)ethyl)-10-(((2S,3R,4R,5S,6R)-3,4-dihydroxy-5-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-17-hydroxy-7-(hydroxymethyl)-5,18-dimethoxy-3,9,11,13,15-pentamethyloxacycloicosa-3,5,7,11,13,15-hexaen-2-one

Purity: ≥95%

Formula Markup: C60H98O23

Formula Weight: 1187,4

Shelf life (days): 1460

CAS Number: 2209112-96-7

Notes: Amycolatopsin A is a macrolide polyketide originally isolated from Amycolatopsis that has antimycobacterial and anticancer activities.{62013} It is active against M. bovis and M. tuberculosis (IC50s = 0.4 and 4.4 µM, respectively) but not B. subtilis, S. aureus, E. coli, or P. aeruginosa (IC50s = >30 µM for all). Amycolatopsin A is cytotoxic to SW620 colorectal and NCI H460 lung cancer cells (IC50s = 0.08 and 1.2 µM, respectively).

• Artikelnummer: CAY31672-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 31672-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK