Amycolatopsin C

Formulation: A solid

Formal Name: (3E,5Z,7Z,11E,13E,15Z)-10-(((2S,3R,4R,5S,6R)-3,4-dihydroxy-5-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-17-hydroxy-7-(hydroxymethyl)-5,18-dimethoxy-3,9,11,13,15-pentamethyl-20-((S)-1-((2S,3R,4R,5S,6R)-2,4,5-trihydroxy-3-methoxy-6-(3-methoxypropyl)-5-methyltetrahydro-2H-pyran-2-yl)ethyl)oxacycloicosa-3,5,7,11,13,15-hexaen-2-one

Purity: ≥95%

Formula Markup: C47H76O17

Formula Weight: 913,1

Shelf life (days): 1460

Notes: Amycolatopsin C is a polyketide macrolide originally isolated from Amycolatopsis that has antimycobacterial and anticancer activities.{62013} It is active against M. bovis and M. tuberculosis (IC50s = 2.7 and 5.7 µM, respectively) but not B. subtilis, S. aureus, E. coli, or P. aeruginosa (IC50s = >30 µM for all). Amycolatopsin C is cytotoxic to SW620 colorectal and NCI H460 lung cancer cells (IC50s = 10 and 5.9 µM, respectively).

• Artikelnummer: CAY33255-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33255-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK