Apiin, CAS 26544-34-3

Formulation: A solid

Formal Name: 7-[(2-O-D-apio-β-D-furanosyl-β-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Purity: ≥98%

Formula Markup: C26H28O14

Formula Weight: 564,5

Shelf life (days): 1460

CAS Number: 26544-34-3

Notes: Apiin is a polyketide synthase-derived flavonoid glycoside that has been found in A. graveolens and has diverse biological activities.{63166,61488,63167,63168} It inhibits Aurora B kinase in a cell-free assay using the human enzyme (IC50 = 12.14 µM).{61488} Apiin (10 and 50 µg/ml) inhibits LPS-induced increases in nitric oxide (NO) release and inducible nitric oxide synthase (iNOS) levels in J774.A1 macrophages.{63167} It scavenges DPPH (Item No. 14805), superoxide, and hydroxyl radicals (IC50s = 68, 390, and 48 µg/ml, respectively), as well as increases the levels of superoxide dismutase (SOD) and catalase in mouse serum, brain, heart, liver, and kidney when administered at a dose of 50 mg/kg.{63168}

• Artikelnummer: CAY34596-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34596-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK