Arachidonoyl-2'-Fluoroethylamide, CAS 166100-37-4

Formulation: A solution in ethanol

Formal Name: N-(2-fluoroethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide

Purity: ≥98%

Formula Markup: C22H36FNO

Formula Weight: 349,5

Shelf life (days): 365

CAS Number: 166100-37-4

Notes: Arachidonoyl-2'-fluoroethylamide (2-fluoro AEA) is an analog of anandamide in which the alcohol of the ethanolamide group has been removed and replaced with a fluorine atom. This substitution adds considerably increased binding affinity for the CB1 receptor (Kis = 26.7 and 908 nM for CB1 and CB2, respectively). It also contributes additional selectivity, in that binding to CB2 is decreased relative to AEA.{7422} However, the in vivo activity of 2-fluoro AEA is enhanced much less than the binding affinity, because the analog remains a good substrate for FAAH and is rapidly hydrolyzed by this enzyme.

• Artikelnummer: CAY90054-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 90054-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK