Formulation: A solution in ethanol containing 0.1% BHT
Formal Name: 1-O-hexadecyl-2-deoxy-2-thio-R-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glyceryl-3-phosphorylcholine
Purity: ≥98%
Formula Markup: C44H82NO6PS
Formula Weight: 784,2
Shelf life (days): 365
CAS Number: 146797-82-2
Notes: Arachidonoyl thio-PC is a substrate for many phospholipase A2s (PLA2s) including sPLA2, cPLA2, and iPLA2. Cleavage of the sn-2 fatty acid by PLA2 results in generation of a free thiol which reacts with chromogenic reagents such as DTNB (Ellman’s reagent) and DTP to allow quantitation of PLA2 activity.{1356} Isozyme-specific cPLA2 activity can be measured by excluding or inhibiting sPLA2 and iPLA2 activities in the assay.