Azelaic Acid, CAS 123-99-9

Formulation: A crystalline solid

Formal Name: nonanedioic acid

Purity: ≥95%

Formula Markup: C9H16O4

Formula Weight: 188,2

Shelf life (days): 1460

CAS Number: 123-99-9

Notes: Azelaic acid is a naturally occurring and saturated dicarboxylic acid with diverse biological activities.{38830,38831,38832,38833,38834} It is a competitive inhibitor of tyrosinase, NADH dehydrogenase, succinic dehydrogenase, and reduced ubiquitinone:cytochrome C oxidoreductase in vitro.{38830,38831} Azelaic acid inhibits the growth and colony formation of B16 murine as well as HMB2 and SK32 human melanoma cells in a concentration-dependent manner but has no effect on CHO cells.{38832} It decreases DNA synthesis, induces mitochondrial damage and dilation of the rough endoplasmic reticulum (RER), and reduces growth of mouse keratinocytes in a dose- and time-dependent manner.{38833} Azelaic acid is bacteriostatic against S. epidermidis, S. aureus, S. capitis, P. acnes, P. avidum, P. mirabilis, and C. albicans in vitro (MICs = 0.03-0.25 M).{38834} Formulations containing azelaic acid have been used in the treatment of acne and hyperpigmentation disorders.

• Artikelnummer: CAY23977-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23977-50
• Green Labware: Nein
• Verpackungseinheit: 50 g
• Mengeneinheit: STK