β-Boswellic Acid, CAS 631-69-6

Formulation: A crystalline solid

Formal Name: (3α,4β)-3-hydroxy-urs-12-en-23-oic acid

Purity: ≥95%

Formula Markup: C30H48O3

Formula Weight: 456,7

Shelf life (days): 730

CAS Number: 631-69-6

Notes: β-Boswellic acid is a pentacyclic triterpene originally isolated from Boswellia that has diverse bioactivities.{30044} It inhibits 5-lipoxygenase (5-LO) with an IC50 value of approximately 5 µM but is less potent than its derivative 3-acetyl-11-keto-β-boswellic acid (Item No. 11672).{6066} It inhibits cell proliferation in HL-60 cells with IC50 values of 3.7, 7.1, and 6.3 µM for DNA, RNA, and protein synthesis, respectively.{38153} In human umbilical vein endothelial cells (HUVECs) transiently deprived of oxygen and glucose, β-boswellic acid increases nitric oxide and increases phosphorylation of enzyme nitric oxide synthase (eNOS).{38155} It also increases calcium mobilization in platelets at concentrations ≥3 µM and induces platelet aggregation (EC50 = 8 µM).{38154}

• Artikelnummer: CAY11693-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 11693-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK