Formulation: A crystalline solid
Formal Name: (5β)-3α,6β,7β-trihydroxy-cholan-2,2,4,4-d4-24-oic acid
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C24H36D4O5
Formula Weight: 412,6
Shelf life (days): 730
Notes: β-Muricholic acid-d4 (β-MCA-d4) is intended for use as an internal standard for the quantification of β-muricholic acid (Item No. 20287) by GC- or LC-MS. β-MCA is a murine-specific primary bile acid.{30824,45190} Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet.{33864} Dietary administration of β-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.{33865}