Formulation: A solution in methyl acetate
Formal Name: (5Z)-7-[(1R,3aS,7aS)-4-butyloctahydro-2,5-dioxo-1H-inden-1-yl]-5-heptenoic acid
Purity: ≥98%
Formula Markup: C20H30O4
Formula Weight: 334,5
Shelf life (days): 730
CAS Number: 109826-53-1
Notes: Bicyclo prostaglandin E2 (Bicyclo PGE2) is a stable breakdown product of PGE2 (Item No. 14010) and 13,14-dihydro-15-keto PGE2 (Item No. 14650). Bicyclo PGE2 is a stable, base-catalyzed transformation product of 13,14-dihydro-15-keto PGE2. 13,14-dihydro-15-keto PGE2 itself is a metabolite of PGE2 found in human plasma at a median level of 20-25 pg/ml.{182,4383} Due to the inherent instability of 13,14-dihydro-15-keto PGE2, it is advisable to quantify it as bicyclo PGE2 to estimate PGE2 biosynthesis or metabolism in vivo.{2571,581}