C16 Ceramide-d7 (d18:1-d7/16:0), CAS 1840942-13-3

Formulation: A crystalline solid

Formal Name: N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl-16,16,17,17,18,18,18-d7)palmitamide

Purity: ≥99% deuterated forms (d1-d7)

Formula Markup: C34H60D7NO3

Formula Weight: 545

Shelf life (days): 730

CAS Number: 1840942-13-3

Notes: C16 Ceramide-d7 is intended for use as an internal standard for the quantification of C16 ceramide (d18:1/16:0) by GC- or LC-MS. C16 Ceramide is a sphingolipid. It incorporates into the mitochondrial outer membrane and forms channels that increase its permeability.{58842} C16 Ceramide levels are increased by PPMP or MAPP in isolated human neutrophils and are correlated with an increase in apoptosis.{19145} It accumulates in the lungs of patients with cystic fibrosis compared with the lungs of patients with pulmonary hypertension.{58843} Plasma levels of C16 ceramide are also increased in patients with acute coronary syndrome, and an increased plasma ratio of C16 to C24:0 ceramide is associated with major adverse cardiac events.{58844} It is also increased in tumor tissue from patients with breast cancer and is associated with metastatic cancer.{58845}

• Artikelnummer: CAY22787-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 22787-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung