C16 Globotriaosylceramide-d9 (d18:1/16:0-d9), CAS 2738376-84-4

Formulation: A solid

Formal Name: N-[(1S,2R,3E)-1-[[(O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl)oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-hexadecanamide-13,13,14,14,15,15,16,16,16-d9

Purity: ≥99% deuterated forms (d1-d9)

Formula Markup: C52H88D9NO18

Formula Weight: 1033,4

Shelf life (days): 1460

CAS Number: 2738376-84-4

Notes: C16 Globotriaosylceramide-d9 (d18:1/16:0-d9) is intended for use as an internal standard for the quantification of C16 globotriaosylceramide (Item No. 24875) by GC- or LC-MS. C16 Globotriaosylceramide (d18:1/16:0) is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide (Item No. 24352).{38975} C16 Globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes.{39721} It accumulates in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease, a lysosomal storage disorder.{38977} Plasma levels of C16 globotriaosylceramide are increased in patients with ovarian carcinoma compared to those with benign ovarian tumors or uterine fibroids.{39712} As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1551]

• Artikelnummer: CAY31199
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 31199-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung