C18 3'-sulfo Galactosylceramide (d18:1/18:0), CAS 244215-65-4

Formulation: A solid

Formal Name: N-[(1S,2R,3E)-2-hydroxy-1-[[(3-O-sulfo-β-D-galactopyranosyl)oxy]methyl]-3-heptadecen-1-yl]-octadecanamide

Purity: ≥98%

Formula Markup: C42H81NO11S

Formula Weight: 808,2

Shelf life (days): 1460

CAS Number: 244215-65-4

Notes: C18 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. It is a minor endogenous sphingolipid produced from C18 ceramide (Item No. 19556) and UDP-galactose in the endoplasmic reticulum followed by sulfation in the Golgi apparatus.{40646} C18 3'-sulfo Galactosylceramide levels are increased in brain tissue isolated from mice with an arylsulfatase A deficiency (ASA-KO), particularly in lipid raft fractions.{43012,36639} Plasma levels of C18 3’-sulfo galactosylceramide positively correlate with disability progression in patients with relapsing-remitting multiple sclerosis using the Expanded Disability Status Scale.{36640} It is also increased in plasma from patients with metachromatic leukodystrophy (MLD).{40650} Brain levels of short-chain sulfatides, including C18 3’-sulfo galactosylceramide, decrease with age in mice and humans.{43012,40648} As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1932]

• Artikelnummer: CAY24863
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24863-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK