C18 Ceramide-d3 (d18:1/18:0-d3), CAS 2011762-82-4

Formulation: A solid

Formal Name: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl-d3]-octadecanamide

Purity: ≥99% deuterated forms (d1-d3); ≤1% d0

Formula Markup: C36H68D3NO3

Formula Weight: 569

Shelf life (days): 1460

CAS Number: 2011762-82-4

Notes: C18 Ceramide-d3 (d18:1/18:0) is intended for use as an internal standard for the quantification of C18 Ceramide (d18:1/18:0) (Item No. 19556) by GC- or LC-MS. C18 Ceramide is an endogenous bioactive sphingolipid. It is the primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1 (Lass1) in mice.{40029} Increased expression of C18 ceramide reduces cell growth in UM-SCC-22A squamous cell carcinoma cells.{13918} It is selectively downregulated in 32 human head and neck squamous cell carcinoma tumor tissues as compared to non-squamous tumor tissues. C18 Ceramide concentration is significantly higher in muscle tissue of type 2 diabetic patients compared with non-diabetic patients and is positively correlated to body mass index and inversely related to insulin sensitivity.{40030} [Matreya, LLC. Catalog No. 2201]

• Artikelnummer: CAY24396
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24396-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung