C18 Phytoceramide (t18:0/18:0), CAS 34354-88-6

Formulation: A solid

Formal Name: N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-octadecanamide

Purity: ≥98%

Formula Markup: C36H73NO4

Formula Weight: 584

Shelf life (days): 1460

CAS Number: 34354-88-6

Notes: C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S. cerevisiae, wheat grains, and the stratum corneum layer of mammalian epidermis.{35021,35022,35023,35024} Cer(t18:0/18:0) is composed of a phytosphingosine (Item No. 20217) backbone amine-linked to a C18 fatty acid chain. Cer(t18:0/18:0) has a role in regulation of apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain.{4469,3512,5031} It also inhibits expression of the allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated murine skin tissue.{35021} Formulations containing cer(t18:0/18:0) have been used used in cosmetics as a skin protectants as they reduce water loss to prevent epidermal dehydration and irritation.{35022,35023} [Matreya, LLC. Catalog No. 2034]

• Artikelnummer: CAY22686
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 22686-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK