C2 L-threo Ceramide (d18:1/2:0), CAS 143615-69-4

Formulation: A solid

Formal Name: N-[(1S,2S,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-acetamide

Purity: ≥98%

Formula Markup: C20H39NO3

Formula Weight: 341,5

Shelf life (days): 1460

CAS Number: 143615-69-4

Notes: C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.{37337} It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide (Item No. 62510). C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) when used at a concentration of 10 μM.{13011} It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.{37336,37339} [Matreya, LLC. Catalog No. 1829]

• Artikelnummer: CAY24386
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24386-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK