Formulation: A crystalline solid
Formal Name: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-tetracosanamide
Purity: ≥98%
Formula Markup: C42H83NO3
Formula Weight: 650,1
Shelf life (days): 365
CAS Number: 34435-05-7
Notes: Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of PLC, appropriately named sphingomyelinase.{3240} C24 Ceramide (d18:1/24:0) is one of the most abundant naturally occurring ceramides.{3931,5862,5395} Ceramides mediate many diverse biological activities, as has been demonstrated in studies utilizing cell-permeable ceramide analogs. A few of the processes regulated by ceramides include apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain.{4469,3512,5031}