C8 Ceramide (d18:1/8:0), CAS 74713-59-0

Formulation: A crystalline solid

Formal Name: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-octanamide

Purity: ≥98%

Formula Markup: C26H51NO3

Formula Weight: 425,7

Shelf life (days): 365

CAS Number: 74713-59-0

Notes: C8 Ceramide (d18:1/8:0) is a cell-permeable analog of naturally occurring ceramides. Unlike C2 ceramide, it is metabolized within cells to generate natural ceramides, often causing a dramatic increase in cellular ceramide levels.{5258} For this reason, treatment of cells with C8 Ceramide (d18:1/8:0) may more closely mimic the effects of ceramide elevation than does treatment with shorter chain ceramide analogs. C8 Ceramide (d18:1/8:0) likely mediates many diverse biological activities, as do natural ceramides. It promotes the differentiation of human keratinocytes{5185} and induces apoptosis of both human leukemia cells and the U937 cell line.{5258,4667}

• Artikelnummer: CAY62540-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 62540-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK