C8 Galactosylceramide (d18:1/8:0), CAS 41613-16-5

Formulation: A solid

Formal Name: N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-octanamide

Purity: ≥98%

Formula Markup: C32H61NO8

Formula Weight: 587,8

Shelf life (days): 1460

CAS Number: 41613-16-5

Notes: C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids.{37368} It increases the amount delivered and toxicity of doxorubicin (Item No. 15007) in cancerous but not non-cancerous cells when incorporated into the nanoliposomal membrane of nanoliposomal-doxorubicin. C8 Galactosylceramide induces proliferation and cytokine production by splenocytes in vitro at concentrations ranging from 100-1,000 ng/ml but has no effect on natural killer T cell production in vivo.{37369} It also activates NF-κB production in C6 glioma cells when used at a concentration of 10 μM.{38647} [Matreya, LLC. Catalog No. 1334]

• Artikelnummer: CAY24346
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24346-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK